Her Saturn and Pluto conjunction falls in your 2nd house so she affects and challenges and possibly destabilizes your security and self-worth, probably making you feel insecure. Her North Node conjuncts your Chiron in the 10th, what she herself needs to develop in this life (north node) somehow highlights a wound or wounds of yours and possibly creates situations where a healing is needed.
Her Chiron on the other hand is conjunct your Jupiter, so she wounds your ability to feel free, expansive, happy go lucky and probably limits your optimism. You may feel pessimistic around her. That conjunct opposes your natal Venus in the third, so it affects how you communicate and will also affect how you feel about yourself.
Her Mars conjunct your Pluto in the 2nd adds to the destabilising factor I mentioned above, except she is Mars so she energizes this and is the "actor" in this situation, activating your Pluto in the 2nd which can make you feel chaotic around her.
Her Mercury is conjunct your Ascendant, and I find it ironic when I see this because you're talking about her (Mercury is communication, the Asc is you)
But, her Sun is in your 12th house. This connection in synastry goes either way. Either they really get along and it's a special, deep connection from a past life, or it causes complete suffering for both parties. Normally people who have their Sun in your 12th are able to see something hidden about you that not many people can see. Are you close or have you been close in the past? Have you revealed things to her that you haven't to others? Or do you feel like she is intrusive in your privacy? Maybe you can't stand her because she is illuminating (Sun) your secrets, your privacy, and making you feel anxious (a byproduct reaction of the 12th house)
Her Neptune conjuncts your 4th house stellium (I have a 4th house stellium like this too by the way, but in Cap/Aqua.) her Neptune conjunct your stellium can either mean that there's a special, spiritual connection, or they can be deceptive towards you, or you to them, and the relationship can be messy and if there are other aspects involved (as there are in this synastry), it can be downright chaotic. Neptune contacts are chaotic when at their worst.
Her Venus squares your Pluto, in the 2nd, so again this is her making you feel uprooted and destabilized around her. Her Venus is her beauty, self-worth, love, relationships, so maybe the way she expresses her beauty, her femininity and her relationships somehow affects how you feel about yourself.
Her Mercury in your 1st squares your Uranus and something else which isn't very visible, but that means that the way she communicates creates tension in your inner life (4th house), and highlights/activates your Uranus in the 4th which can mean feeling uprooted and possibly unstable but wanting to be stable.
Overall there are some harsh aspects involved. Most of it impacts your Pluto in the 2nd and it brings out things that you would rather keep hidden. Around her you might feel like overthrowing everything although if you don't, you're probably subconsciously aware of the fact that she causes you insecurity and general unrest. This subconscious facet is highlighted because of her Sun in your 12th. I think she subconsciously exposes your fears and highlights them to you, making you uncomfortable.