For example; your opposition between Pluto and the Moon can be overcome by using the sextiles from pluto to venus and neptune/mars.
You can use the areas ruled by the houses ruled by the planets. For instance, your Neptune rules your 9th house which is the house of studies, higher education, religion etc. Your mars rules your tenth house which is the house of career etc. And your Venus rules your 11th house. So in order to overcome the Pluto-Moon opposition, you will have to work with Venus, Mars, Neptune, and with Groups and the public and career (10th and 11th house) and also with higher education (9th house) whatever that may be is difficult to say.
When you finally overcome it, you can expect a great deal of revitalization of Pluto and Moon in your chart, with added joy to the 5th house and the house of the Moon.