Astrology is largely an historical artifact. Unless someone is doing path-breaking new research, we mostly deal with astrology handed down to us from times when gender and social class rules were clearly and rigidly defined.
For example, the Hellenistic astrologers thought that a strong/afflicted Venus in a chart would make a man "effeminate." It was considered a stigma to be the child of a slave or to marry a slave, no matter how high one rose in life.
Until the past few decades modern astrology had a signature for gay men: Uranus square Mars. Then it was noted that many heterosexual men also have Uranus square Mars, and many gay men do not. I know one lesbian with Venus square Uranus but I don't that this signature works any more reliably.
Ironically during the 19th/early 20th century, and perhaps earlier, Euro women formed intense friendships with other women, and Euro men formed intense friendships with other men to the point that they wrote love letters to one another. (Which have been preserved.) It isn't clear if these attachments were consummated sexually, but falling deeply in love with someone of the same sex seems not to have raised many eyebrows; notably if these people married someone of the opposite sex.
A well-known example was Eleanor Roosevelt's exchange of love letters with her long-time "friend" Lorena Hickok.
https://people.com/books/new-biography-explores-eleanor-roosevelts-romance-with-a-woman/
Gender has always been a fluid topic so far as I can determine. We could go on with some past societies' traditions of creating eunuchs as palace guards or contra-tenors (male sopranos.)
Today is just our most recent iteration. Astrology will catch up eventually.
We cannot tell from a horoscope, without additional collateral information, whether the person is male or female.