Since I have been around for awhile, I have had several planets change directions. When my progressed Mercury went retrograde, I was serving on the boards of trustees of some not-for-profit volunteer organizations and had been for some time. That all ended, and I am not active in any of those organizations any longer. However, I have more time to devote to astrology.
When progressed Pluto went direct, I found employment with a large company and began making more money. From a very frugal condition I became very prosperous, paid off all loans, bought a new car for cash, obtained a good computer and astrology software. But I do not practice conspicuous consumption.
When progressed Mars went direct I rather suddenly found myself facing some lawsuits and and other legal issues all unrelated. Some went to trial, but I either prevailed or fought them to a stalemate. That seems to have all ended now. I have natal Mars conjunct the descending node which is said to allow the native to prevail in lawsuits.
When Saturn went direct, I had to take another job with my company due the bad economy. It proved dangerous. I was exposed to some unpleasant contagious diseases, had accidents, and while driving home from work, I was hit from behind by a SUV moving at high speed. My car was destroyed, but I was rescued intact. I seem to have recovered from all that now, and have returned to my better job. My natal Saturn is exactly conjunct the fixed star Mizar which is very dangerous with malefics and can cause accidents.
Yes, I can say that when natal planets change directions by progression that there are real and visible effects.