Traditional text says if 5th lord in 7th or 7th lord in 5th person either be unmarried or will be issue less . your aunt has 5th lord in 7th , despite of 5th house un afflicted, it spoiled childbirth . but other things got affected . guru in 12th , 5th from guru is sat ketu aspected by rahu , 5th lord in 12th of loss . guru is in rahu star etc etc , i know these technical things no need for you , its my duty to make clear . both husband wife house of children's afflicted .
There is one chance in this year and nxt year . because sat has transited to 5th in both nativity , but wife's 5th house some what good . 9th lord in 5th . only hope for now . so before 2023 she may get . after that no chance . even though coming periods connected with 5th house .