I'm not sure I'd say it's the worst, but it is generally a difficult indicator. Additional considerations, as Catatonia has mentioned, are certainly very important and valid!
One should also consider Saturn, functioning in it's positive, higher resonance, indicates stability, longevity, and solidity. If the function of Saturn in the relationship overall is positive, and the natives have integrated Saturn's energy in a more positive manner, it could indicate a serious, committed nature to the warmth and love of the other. One the negative, Saturn's cold crystallizing side can drag down the other's sense of warmth and love through it's overly negative attitude, pessimistic outlook and excessive doubts/fears.
Rules for Planetary Pictures basically takes the totally negative look on anything to do with Saturn (and the other "malefics" as well) but here's the guidelines provided:
MO/VE=SA The forsaken woman. The widow with children. The sick mother. Separation from the mother.
MO/SA=VE Unfortunate mother. All alone in marriage. Wishes which come not through. Unmarried mother.
VE/SA=MO To make a loving woman feel sad. Forsaken women.