For me, looking at the composite in whole sign, I find the difficult and chaotic South Node in the 1st whole sign house, and I find the often changeable and revolutionary Uranus within 2 degrees conjunct the South Node-which I consider to be a very difficult indication, involving as it does the "composited personality/essence" house (1st house); Jupiter/Neptune/ascending degree partile conjunction is also a very mixed indicator, showing a strong Neptune influence (can be romanctic delusions, illusions) affecting the "logical mind" (ie, Jupiter); mixing this with the South Node+ Uranus conjunction, all in that first house, seems to indicate a great deal of possible trouble and difficulty, in the potential relationship.
Star connections to elements of the first house are also unfortunate:
1) Han, a highly disruptive star, is conjunct in longitude Uranus (Note: some might give Antares here, as the more significant star; also quite disruptive especially connected with Uranus)
2) Kuma, which star channels in the often difficult influences of the constellation Draco, is conjunct in longitude the South Node
3) the very unfortunate Sinistra, is conjunct in longitude the ascending degree/Neptune/Jupiter partile conjunction-this is the most disruptive of the star connections here.
For me, these star connections with the elements of the first house ALONE would lead me to conclude a very likely difficult (or worse) relationship potential.