A lot has to do with how old you are....your family and professional circumstances and more.
If you have had other oppositions to your Moon in the past from heavy planets, you might be able to look back on those times to see how you responded to them.
If Uranus today is about to oppose your Moon, then your moon is in Libra, but you don't say which house contains the moon.
Also....there are OTHER aspects always happening. the more other transits working at the same time, the more complicated the issue becomes.
IF your Moon is square to any other planet natally, they there will be more issues than just the opposition.
If you post your chart it would be easier to know how difficult this will be.
Remember that Uranus will enter Taurus later this year, temporarily and then retrograde back to late Aries....will it oppose again or not? This "length of transit" is important when dealing with the question, "how difficult will this be?"
If you already have emotional issues this can bring them to a head - or if you're in a relationship this or any other major opposition can bring out issues not dealt with before.
LIN