The Nodes have to do with general direction in life that can unify inner/outer (moon/sun). They do not indicate vocation, nor do they indicate material matters, just orientation/attitude. But of course, you will want to choose activities and occupations that don't obstruct the direction they indicate.
Example:
If you had your S.Node in the 7th house / N.Node in 1st this would generally indicate that as time goes on you will want to emphasize more self-directed activities and personal growth that it not dependent upon or interfered with (modified by) contacts with others.
The problem is that many birth charts are just not accurate enough on the Asc to do house-related interpretations of the Nodes. Sign position of the Nodes is very general, but still relevant. My own S.Node in Virgo indicates a past of orderliness, detail-orientation, practicality and critical views of life/self/others that I must draw upon in order to make use of my basic talents to grow and move towards other things. N.Node in Pisces indicated the need to learn a more spiritual, open-minded approach to life and others.
The difficulty with many of these pop astrology books is that they try to squeeze the big truth of grand self-realization out of just one chart factor. Can't be done.
Your chart:
S.Node in Cancer indicates starting with a sense of the importance of security and subjective personal needs and the importance of the roles of mother/women. N.Node in Capricorn indicates moving more towards constructive aims and self-parentage with a more proactive, time-aware look into the future rather than relying on the familiar or maintaining sentimental preferences.
With your N.Node nearly exactly parallel Neptune, you may have difficulty feeling you have a clear enough vision to move forward. So don't rely on vision. Relying on feeling your way, as indicated is more natural to you when looking at the S.Node. Don't treat the two poles as contradictory opposites. They are not. They are two balancing points on a continuum.
Notice that Mercury is square your Nodal axis. This is your key: Think, write, communicate to stay aware of your own internal resources and natural abilities and to keep yourself moving forward. Don't fall incommunicado. At times this approach might seem to get your in a bit of trouble. Just consider you may have lacked clarity (square Neptune).
In your case, because the N.Node is so tightly parallel Neptune, it could benefit you to get involved in some Neptunian activities to develop in a positive direction. Not on the assumption of it leading to a vocation/money making. Pull practical expectations out of it and just see where it goes. Painting, dancing, poetry, film making, etc, etc. Whatever Neptunian activities you think could help you. Although it does also indicate fantasy, hypnosis.