This would be a good time to focus on your north node: where your growth lies. You are getting a celestial "kick in the pants" at this time. Note that the square is equally to your south node, so you should feel challenged to get out of your comfort zone, as well.
If your north node is in scorpio in the 2nd, two things to pay special attention to are your money and your sense of values. Traditionally the 2nd is the house of money, so this would be a good time to study personal finance management; and to get your personal resources in the best shape you can. Are you familiar with guru Suze Orman? She's a very wise, funny lady, with a website, books, and TV program designed "for the rest of us" on how to handle our money.
Note that oftentimes the NN moves us well out of our comfort-zone, so it is OK to challenge yourself.
Sometimes the money situation of people with a 2nd house emphasis actually works out OK, but they just are not very interested in money. If this is your case, look at your sense of values. Scorpio is a truth-teller, and this would be a good time for some personal stock-taking.
The 10th house indicates your vocation in life, and Leo is about leadership, so these would be other areas of life to consider.