well, a planet t-squaring the lunar nodes has massive importance.
first off, the south node reflects what we've done and where we've been in past lives. the north node represents our path for development, and where to cosmos is guiding us. I'm guessing you know this already, but if you dont, the rest of the post will make more sense now.
when a planet t-squares the nodes, the following considerations should be made:
a) the planet is in a state of dynamic flux. It's in conflict both with the past and the future
b) to get to this state of flux, you've been working on it heavily in past lives.
c) since its not only in dynamic aspect to the past, but the future, your not done working on it.
d) since the aspects are dynamic (conflict, need for resolution, etc) and both the past and future are involved, it becomes a focal point for this lifetime. a planet t-squaring your nodes can not be bypassed; it _must_ be addressed during this lifetime.
e) not only must it be addressed, but its also the primary focus of this entire lifecycle.
f) the dynamic aspects between the planet and the node assure you that situations to develop the planet's qualities will manifest, as fated/destined situations. there is no escaping it. if you try, you wont succeed.
g) kharma is indicated, but can be positive or negative -- just because the aspects are dynamic (hard, conflicting, whatever you consider it) doesnt mean bad karma. in fact you should consider yourself lucky to have this level of interaction between the nodes and a force you really need to work on; its a gift!
h) if you attempt to avoid working on the planet, transits by the karmic enforcers (saturn/pluto, but in a lesser sense mars too) will be extremely difficult for you, and will force you to the planet squaring the nodes.
i) the overall picture of the nodal axis will tell more about the situation, and other planetary aspects, especially conjuncts, to the node will reenforce the picture.
i have a massivly difficult nodal configuration myself.. my sun t-squares (by only 2 arcmin!) the nodes with mars conjunct north node and moon conjunct south node. it speaks for my important need to work on my ego... with the south node in pisces, my past life/lives have been spent breaking down my ego, giving myself up to a higher cause. in fact, im pretty sure i was a monk or other sort of spiritual devotee in prior lives, and this life i must pick up the pieces of what i destroyed (my own ego, for self-purification reasons) and and start from scratch.
and, this is exactly how my life has been. when i hit my teenage years, well before i knew anything of this configuration, it was natural (south node comes so easy, for it's been done so much in the past!) to start breaking down my ego again.. it wasnt until later (recently, actually) that i realized i need to be BUILDING my ego, and ever since i realized that my life has taken a 180 from "going against the current" to "flowing with the energy" -- fated events tried so hard to keep me from breaking myself down any further, essentially i was deadlocked. once i realized i had already been through the self-purification i thought i needed so badly, its as if the black tinted window i couldnt open just shattered before me and all the light just came pouring in.
those of us with planets t-sqaring the nodes have a very important soul mission for this life which we must not deny... we also have the blessing to complete it, and the strength to face very difficult lessons about ourselves.
the placement, by sign and house, of the object t-squaring your nodal axis will be very telling of the sort of energy, and it what aspect of life, you will find success in developing that object. for me, the sun is in sag, in the 11th house of uranus. higher beliefs and revolutionary spiritual concepts. nowonder im an astrologer!
I hope that helps, if you want to pick my brain please feel free - ill give you the best answers i can.