Moon is opposite Chiron, so internal emotional pain regarding the home or childhood is life-long (chiron is not in the 4th but very close to the IC and Moon rules the 4th traditionally). Mars is in very close trine to Jupiter/Uranus, making it very easy to overdo intoxicants. Transiting Neptune is semi-square Neptune, triggering the urge, plus natal Moon is square Uranus/Jupiter so he is always tempted to use intoxicants as an emotional crutch. Saturn opposite Mars close saps his energy and will to resist. Lately Transiting Uranus has been opposite the Sun, creating more events to trigger the desire. This is a life-long problem that will continually be triggered by some transit somewhere.