The most important is your Ascendant your appearance, your mask to the world your physical body, North Note is also important because it shows your goal in this life your life´s path, but in a more subtle way and is a silver line in your current life, where you came from South Node(Past Life) and where your are going in your current life (North Node). Ascendant aspects would i put as more important than the North Node, bevare we talk about western astrology.
Rahu/Ketu the North and South Nodes in verdic astrology have another meaning and can be very malefic with or without aspects. But i´m not an expert North Node/ South Nodes and has not studiet the relationship between Ascendant and North Node, other than if there is a aspect to the ascendant in the horoscope i am studying, so maybe you can enlighten us