some points to consider:
1. i have found that when pluto is so directly on the ascendant the answer is a 'no' or 'there will be a extensive delay in the realization of this'. pluto here also shows the mental pressure you are on that are imposed on to you from the outside
2. south node in the first house, pluto, mars..all the malefics are there- you have got some meditating to do my friend- the first house represents you and it seems you have got some negativity going on.
3. plus side: you are represented by saturn- who is domicile- so still a strong position, also shows that working hard/having a good work-ethic/practical understanding of the situation is what is important to you
4. 10th house- 10th lord is mars- he is in the first house- which is not bad at all- its actually good it means the 10th house things now come to you- BUT there is a square from venus that just passed- and another square from mercury coming up. another good thing about the 10th house is the fact jupie jupiterius is there- and thats always good
5. 6th house of routines and work etc- is ruled by gemini- who is ruled by mercury- and he is in scorpio about to square the 10th lord- mars- who sits in house 1. i feel there might be a resolution to this quite soon- although perhaps because of the square aspect it wont be the smooth easy fast resolution-type
6. mentally ready- so for mentally-things we look at the moon. moon is in 11th house- in sagittarius, just got out of detriment, and will sextile 10th house lord mars soon..THAT does look a bit more promising!
there is something to be said about uranus as well i cant seem to put my finger on it