It depends on the condition of the planets in question, as well. A dignified Saturn (say, exalted in Libra) on the MC when entering medical school would be an excellent representation of the best aspects of Saturn (responsibility, discipline, etc) as well as the grind of medical school in general.
A poorly aspected Saturn would be something else entirely. Jupiter in fall (as it is now in Capricorn) is not necessarily a good thing, either. But as a general principle I would rather have the benefics on the relevant angles than the malefics, unless, as mentioned above, the malefic is in its sign of exaltation, which changes the timbre of its significance.
I agree this should go in electional astrology, however, so I'm moving it.
AG