Here is my take on the matter:
You are signified by Saturn, exalted, in the 10th. I'd say that you are good where you are right now. Saturn exalted shows a person living above or slighty out of there own means, it's an exaggerated position but, nonetheless, a favorable one.
Venus, the ruler of the 10th is trine to you, Saturn. This is also very fortunate for you present position.
Now, as for leaving all this and starting your own business, we look to the Moon, for it shows your next action. We see the Moon is quite detrimented and about to square Mars in the 10th. Mars would signify the business you want to start as well as what you plan to do. We can see, right now, is very weak and not well disposed to you. Mars also has no assistance from any other planet to make the connections for it that it needs in the world or to strengthen it in any way right now.
I would say that, right now, stick with your present job and nail down the details and ramifications of starting your own business. Right now, appears not to be the best time to make that leap. Or, do both, though, that may be quite challenging I think.
Venus trine Saturn is a successful business indication but, with the Moon squaring Mars I would wait a bit before leaving your current job for your own business. It may also be that success or further success will come, someway, through your current job.