OK, so if I look at your grandmother's horary:
First house: I would have turned the houses differently, but Rex E. Bills, The Rulership Book gives the first house for the grandmother of a man. Ruled by Venus. The house itself looks OK, but Venus is in detriment. But it's not entirely helpless: in its own face and angular.
6th house of health: ruled by Jupiter. Venus applies to a nice trine with a domiciled Jupiter. Jupiter, appropriately is in the 3rd house which rules the lungs.
Doctor, 7th house, ruled by Mars. After leaving Jupiter, Venus applies to a sextile with Mars.
Outcome, 10th house Ruled by the VOC moon.
So within reason, and allowing for her health condition going into her crisis as well as her age, to me a lot of the chart looks good, but I wouldn't expect much change in your grandmother's condition.
Probably I've missed a lot, and as I said, I don't want to be in the business of giving false hope, so please let us know what happens.