It depends greatly, on what the woman wants out of the act. If it's for money, then look for negative 2H and/or Venus. If it's for sex, negative aspects between Mars/Pluto and bad 8H. If it's a desperation for companionship, negative 4H (childhood issue), 12H Venus or Saturn (a fear of being alone) and 7H Saturn (a difficulty in establishing relationship). If it's for fame (like she thrives in the infamy of being a man-eater or wants to use a man to advance professionally), bad 10H and/or MC, the Sun may also involve (I'm thinking that Capricorn, Scorpio and Aquarius are the most likely to do that).
And then there's a kind of women who just like the feeling of hooking up with married men, like it's some kind of adventure. Then it could be negative Jupiter, or a Sun/Mercury sign that likes to experience everything. My suspects are Gemini (doing this as a cold intellectual exercise), Sagittarius (thriving in over-the-top experience) and Aquarius (likes strange experience)