I am not good at reading chart or putting interpretation into writing. This is my practice reading so just bear with me
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I would like to suggest to have a look of Helen Keller's natal chart. She was famous enough, with reasonable amount of information about her and she had already passed away. With no planet in 12th, but she had suffered from lost of hearing and eyesight (form of imprisonments due to disabilities also lived in insane asylum ) since early age. But however she wasn't truly trapped inside of this prison but instead she was free in her own ways and achieved greatly in life. She has high focus in 8th house and her rulers of 12th & part of 1st houses are Mars and Pluto (Placidus system).
Link for her Biography:
http://www.astro.com/astro-databank/Keller,_Helen
Helen's ascendant is 25 Scorpio 20 at later degree. Taurus Pluto (Detriment) is at her open enemy house conjunction with descendant opposite to Ascendant.
She has no planet in 1, 2, 3, 11 & 12. 9 planets are located on the right side 5 above, 4 below the horizon remaining Uranus is at 10th conjunct MC in Virgo Cusp based on sign, Uranus is ruled by Mercury. Uranus and Moon are both at angular houses in 10th and 4th. Moon is in her own house, her family background was very wealthy and parents were well educated and her mother was inspired by education for blind and deaf woman which later alternated Helen's life. Moon semisextile Jupiter, Jupiter trine Mars which Jupiter influenced Mars in both positive and negative ways I believed. After all Mars is an malefic expanded by Jupiter.
Saturn (Fall) the other malefic is opposition to her Mercury in 9th; I believe Mercury is the ruler of hearing??
NN is in 2nd, SN is in 8th house which Sun is conjunction with SN. Sun is the ruler of eyesight. Sun is at the near midpoint of Pluto and Mars, two malefic. Virgo Uranus another malefic sextile Sun at 10th and Uranus trine Saturn, Saturn opposite Mercury; Uranus conjunct with MC, lost of eyesight and hearing were possibility beneficial factor for her development of her final achievements. Uranus conjunct MC is the ruler of 3rd house of communication and Mercury is the ruler of Uranus and Mercury is at 9th house of higher education. Mercury is the ruler of hands, writing, teaching and communication.
Both Pluto and Mars ruler of 12th and partial of the early degree of 1st house were perfected their aspects at the age around 2 years old. Mars square Neptune perfected at 2S and Pluto opposite AC at 2A which suggest as Markers of events at around the age of 2. Pluto in Taurus, Taurus is the sign that rules vocal cords and throat.
Oh well sorry about my long description of the chart, my point is no planet in 12th house, but rulers of 12th Mars and Pluto both have significant indication of her imprisonments due to lost of hearing and eyesight also her impaired ability of speech. But there is no planet in 12th, and Scorpio is a sign of transformation/regeneration/rebirth. No doubt she still experienced extreme level of imprisonments due to her physical body (Ascendant & part of 1st house) but she was not truly and fully in prison due to her own disabilities. In fact, because of all these disabilities and hardship from the 8th and malefic planets (which also proved the positive effect of malefic planets), she achieved much higher than regular healthy individuals. Her whole life is a inspiring true story to all of the disable people. Although I must say all due to the power of her 4th house, wealthy family, supportive parents, good education from early age with enough money to learn and to maintain her living. With such a well positioned Moon, she had the emotional ability to transform her own disabilities to the most positive way.
I believe in reading the whole chart and looking at the rulership of 12th house. I hope I managed to make my points clear to you guys...