I think it is your Vesta quincunx the ASC. The ASC is where the outer world comes into your sphere of consciousness, and Vesta is where we put energy, thoughts and beliefs into the Universe for manifestation. Thus, your thoughts and beliefs are negatively influenced by the outer world, and as you absorb this negativity, you create a negatively-influence reality with this. As the ASC is in Cancer and the Moon is square the Sun, and the Sun is sesquiquadate the ASC, your core being is also negatively aspected by the outer world, which effects you in a deep emotional manner, which further sends negative emotion to the Universe for manifestation as your reality. These manifestations come out the Vertex, which - ta da - is conjunct your Moon. A nice little vortex of negative creativity. The Sun sextile Neptune just lets you spin fantasies about why this is so and justifies it in your mind, but it is giving you a false sense of reality.