Asc. lord means, Lord of the person whose (Body, mind, self) birth chart we are talking about. Of you.
Your specific question was related to profession, second question was related to you get agitated, so this reply was accordingly.
Suppose you are sitting in between two malefic/type of persons, then can you behave normally.
The same thing is with you in this chart.
Mercury is shubhi grah in your Lagna, means you are intelligent, supposed to be soft spoken, but two planets in the side of you are disturbing you.
That means, you have to give more power to Mercury (BUddh).
If you are going to Ganpati ji, then good, you can give grass or any green eatable to cow for 5 Wednesday (If you feel like doing this or can give daan of green Moong dal to any of the needy person on wed.)
MD means your Mahadasha.