What do you lovely people think of drugs? By those I mean the illegal ones such as Cannabis, cocaine, heroine etc. Personally, I think Cannabis should be legalized and heroine isn't as bad as most think. In fact, did you know that Heroine is close to Morphine?
From a chemical standpoint, morphine and heroin are quite similar. In fact, heroin is simply diacetylmorphine, a morphine molecule with two acetyl groups attached. This has the effect of making it more lipid-soluble, which makes it cross the blood-brain barrier more easily.
Methadone, however, is synthetic (whereas morphine and heroin are derived from the opium poppy Papaver somniferum). It has a different chemical structure from the naturally occuring opiates, and some different effects as well. It has a longer duration of effect compared with other opiates and produces cross-tolerance towards them, which are two things that make it useful in treatment of opiate addiciton. Heroin does not occur naturally in the poppy and as such is classified as a semi-synthetic opioid. However, it bears much structural similarity to morphine, whereas methadone does not.