My Husband has uranus and pluto in 7th virgo natal. (along with sun conjuct tight with pluto, mercury is there in there as well).
He had a marriage at an early age and divorced. We've been married over 19 years, we were married when he was in his late 20's.
I use whole house for his chart, I tend to use whole house unless there is a stellium in the 12th house or the 6th houses. Then I will toggle back and forth between whole house and placidus and use intuition or knowledge about the individual to determine which chart is best for natal.
In his chart, his placement of the moon is more important that looking at the uranus or pluto in his 7th house.
I would think that we would have to look at the aspects and the chart as a whole before we could really say for sure how the uranus in the 7th will manifest.
In our synastry chart my pluto kisses (is exact conjuct) his uranus. This was a life changing, deep soul changing relationship for both of us. I used to tease him that we went through hades with gasoline soaked underwear to get where we are today. But we did it and neither of us are the same person we were when we married one another. We are better, stronger and so much more as a duo than we were as singles.
Perhaps those with uranus or pluto in 7th should look at the aspects and the chart as a whole to see if that's what they need---someone to life them out of their life, spin them around and shoot them towards the stars? Just a thought.
(I'm new here, hello everyone! sorry to butt in