Re: Transit Pluto opposing natal Uranus
Byron, I couldn't access your chart so can't make specific comments about your current transits but the fatigue, alcohol intolerance and betrayal by friends sound like Neptune/Pisces issues. You mentioned a stellium in Pisces--are any of the planets in early degrees? Transiting Neptune is in Pisces now.
Also, if you're sixty then transiting Saturn is still hovering around your natal Neptune and although the orb between your natal Saturn & Neptune is wide I'd still consider them conjunct at birth especially if you have other placements, maybe your Aquarian Sun to strengthen the connection.