I might have something to say about it.
Pluto and Neptune are too slow as planets to do any influence in your natal. However if an important planet passes there, it could start making some influences on you.
On the first glance, the Pluto/Neptune with Mercury yod deals a lot with the way you think and what you believe ( Especially what OTHER people want you to believe).
From the Mercury part of the aspect, looks like you were born kind, soft, dreamy, meditative. YOU WANT TO SAVE THE WORLD!! ( just kidding on the last part ). It's a great Mercury, but I'll focus on the quincunx more.
Anyway yods aren't bad aspects, they just make us confront the jamais-vu of our life or your psyche in particular.
As an Aquarius Mercury you always try to judge the "What Measure is A Non Human" or "What Measure is A Human".
Pluto and Neptune can be harsh because they'll challenge your values while using your humanistic way of judging values. ( they will play by your cards ). They will challenge your way of thinking, in how to act in the face of immorality, injustice or inhumanity.
It's like the devil trying to use the bible and theology to attack the church and succeeding. The same way happens with you, people will use their own interpretation on what is right or what is human.
Stand your ground.
You'll notice the values and virtues of life are starting to reverse, you'll see there is no justice, there is no goodness or generosity.
People will try to manipulate you by saying " Oh! It's Because Your Family Taught You The Wrong Way " or " Oh! God Made All This Suffering " so they enrage you and activate your anarchy side of Aquarius.
When that happens, remember, meditate and ask yourself " why did this happen ? ", " why did I behave like that ", " how do I fix it ?", " Was it human enough ?. The trigger of the enrage could be someone you trusted and it's not from your natal family or childhood. ( Don't blame a cute North Node
Stand your ground, not everything that flies is edible.
I SUX AT ASTROLOGY please don't keel me.