Somewhere between 40 and 42 yrs of age, we have transit Uranus in opposition to our natal Uranus. Then, look also at how your natal Mercury/Moon are being currently affected by the outer planets, esp Uranus (high-strung sudden spurts of nervous energies. Check also for any connections between Uranus and Mars natal vs transit. Btw, speaking about Uranus and Mars, there has been a conjunction between these two planets in the current skies, though now loosening up. Is this conjunction falling in your 3rd/9th house, or making a square to planets there by any chance?
The above are just some thoughts, but there could be many other astrological reasons for those panic attacks. The best would thus be, if you could post
your natal chart with the transits for Apr 27, so people can have a look.
Also, since you haven't provided any astrological interp from your side, I will have to move your thread to the 'Greenhorns Lounge'.
Oh, and a belated happy birthday.