Like Angelina Jolie, she has Neptune in sagittarius, in the 5th house. However, she has Jupiter in the 11th.
The above quote says quite a bit to me as regards adoption of children, but there are also other configurations in this connection that I will mention below.
The eleventh house is connected with adopted/step/foster children, and Jupiter in there would clarify the need to grow and expand through this action. This Jupiter of the 11th also aspects both the native's lights showing that this urge is ingrained in this native's personality, more so as the Moon sits in her first. Also, the 11th house indicates, besides society and friends, brotherhood and humanity, so the native might 'hope' (also 11th-house matter) to do, in this way (esp as she has adopted kids with special needs), her bit for humanity (in comparison to most of us, who only brag about such things) and, through that, grow spiritually (both a Jup and Nep theme).
Neptune in the 5th has an inspirational influence in this area of life (arts, also children) and is also connected with adoption. Neptune here could make the native very sentimental, compassionate and selflessly giving towards children. This native's Nep also trines (supports) her Moon, adding on to her sentimental 'motherly' emotions (Moon) towards children (5th house involved), which must be of prime importance to her (Moon in 1st). One must also always bear in mind that, since the 5th and 11th houses lie along the same axis, planets in any one of the two houses automatically influence the opposite-lying house. Nep in the 5th might here be reflective of the fact that perhaps something about the family-origin of the adopted kids (read this in context of 5th and 11th lie along the same axis)is 'not clearly known. Nep in Sag is a very broad generational aspect, shared by millions around the world, so I will leave it out here.
Moon (motherly emotions/desires) in Leo would, on its own, indicate very warm and generous emotions, which are part of the self-expression (Leo and 5th house trait) and need to be openly expressed/demonstrated (Leo). Again, here it will help to bear in mind that Leo naturally rules the house of children (5th) and Leo's are not only known to be somewhat child-like themselves but also for their love of children (there are exceptions to all rules, of course), look also at Madonna's chart in this context (and child adoption). In this native's case though, the openly-expressing-the-emotions' part could be a bit inhibited or restrained due to the tight Sat-Moon conjunction in the 1st.
Sun in the 6th house of service to others can also be taken into consideration here as regards the topic. Note also that Mars (trad. ruler of Sco), ruler of the 5th-house here, is also placed in the 6th.
Finally, interpreting the placement of Ura and Plu in the 4th house of home and family tells me that there is something different, even progressive (through Ura; child-adoption certainly falls in this category) as well as transformational (Plu; transformational for both sides: mother and child) about this family. Pluto in the 4th could also reflect here certain heavy problems within the family, which are fairly understandable in case of children with special needs.
This native's chart is a perfect example of how many factors in a chart combine to reflect one particular aspect of the native's life.
Hope this helps clarify matters a bit.