The First House is the rising sign house and the childhood house. Planets in this first house under stress (square opposition or inconjunct to other planets), Saturn, or planets in Aries, will often reflect a Karma with yourself or with childhood. Anything to do with the self, meaning self-esteem, appearance, even vanity. There could be a personality Karma, a character Karma, or an identity Karma, especially during childhood, leading to unprocessed experiences. As soon as we become conscious, we realize that we are in negative territory. That is why we are forced to grow up quickly with planets in the first house, in Aries, and especially Saturn, which magnifies this effect.
The Second House would be a Karma concerning money (nine times out of ten), value, self-worth, love, or what is important in this life-cycle. These individuals sometimes appear agnostic to the world and do not appreciate the real meaning of love. There can also be obsessions with the material so the spiritual side is of often lacking.
The Third House would show a Karma with the mind. Planets in the third house under stress, in Gemini, sometimes indicates mental instability, psychological Karma, or mental illness if one is not strong enough to handle this kind of Karma. Some of the communication problems could be with brothers, sisters, neighbors, or even teaching. It is either that they're not heard right or they don't hear things the way they should. This extends to relating things to other's that is wrong.
The Fourth House planets or afflicted planets in Cancer can show Karma with the mother, feelings, residence, and security. Saturn is detriment in Cancer, so any tendency to have an emotional wall will be further strengthened. The fourth house also signifies past lives, so when you get your button pushed and have no idea why you react the way you do, it could be from a past life.
The Fifth House planets or afflicted planets in Leo would be a Karma with the family or creative endeavor, with power, and authority. In Leo, any Karma will be with the father, or no children, but in the fifth house it is with creativity, pets, enterprises and children.
The Sixth House planets or afflicted planets in Virgo, epitomize major Karma concerning work situations, health if you don't maintain it, and service due to a lack of it. It may also affect your judgment, and analytical ability.
The Seventh House planets or afflicted planets in Libra would epitomize lessons in love or relationships. A lack of balance between yourself and partners indicates another type of Karma too. Some of the problems that can manifest here concerns the obsession to get married, but often find themselves getting divorced. A heavy Karma could indicate a persecution complex.
The Eighth House planets or afflicted planets in Scorpio would show a major lesson in life concerning sensitivity, deep emotions, love, sex, intimacy and transformability or lack of the ability to transform, change, or metamorphosize. As with other water signs, the emotions can be contracted, and restricted. It's easy for these people to be celibate. There may be jealousy and obsessions with death or problems dealing with others dying.
The Ninth House planets or afflicted planets in Sagittarius would show Karma concerning philosophy, freedom, religion, justice, travel or lack of it, and sometimes being anchored to ones' life, work, job, family, home and responsibilities. Sometimes lessons concerning happiness—a contraction of happiness—are shown, Karmically speaking. That's why these people tend to get very moody and depressed.
The Tenth House would show a Karma with external aspects of life. Planets in the tenth house under stress, in Capricorn, would epitomize Karma with ones' career, authority, practicality and ambition.
The Eleventh House planets (under affliction) or planets in Aquarius or at least two in either signs or house would epitomize the Karma concerning groups, friends, goals, organization and direction in life. Also humanity or lack of it.
The Twelfth House planets or afflicted planets in Planets in Pisces would epitomize a Karma with oneself, in being you're own worst enemy. It is a very emotional Karma, indicating self-destruction and hidden events. Hidden events are not readily visible and can effect your life in the long term, because a decision or commitment was not made when it should have. Also there can be Karma with enemies, mankind, institutions, and hospitals. Saturn in Pisces or the twelfth could be a Karma with people that definitely identify themselves as your enemy, and who would also want to hurt you. It's also a lesson in emotions.